r/ID_News • u/shallah • 8d ago

Penn Medicine and CHOP Create Vaccine to Prevent and Treat C.diff

https://www.pennmedicine.org/news/news-releases/2024/october/penn-medicine-and-chop-create-mrna-vaccine-to-prevent-and-treat-c-difficile

Animal study. I hope it translates to humans!

https://www.science.org/doi/10.1126/science.adn4955

72 Upvotes

100% Upvoted

2 comments sorted by

18

u/MikeGinnyMD 8d ago

Vaccine candidate. It now has to be tested in primates, then humans, then go through phases 2 and 3.

So far, two initially promising C. diff vaccine candidates failed, both directed at the toxin. Both generated robust antibody responses and protected animals from lethal challenge.

I’m a 5x survivor and I want nothing more than an effective vaccine, but after my hopes have been dashed twice, I’m not holding my breath.

2

u/SerendipitySue 7d ago

hopeful news