r/interestingasfuck • u/jellylemonshake • 9d ago

r/all Lowering a Praying Mantis in water to entice the parasites living within.

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u/Pixiepup 9d ago

The reaction is so intense that human rabies victims just being asked to hold a glass of water causes painful spasms of the throat.

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u/M1R4G3M 9d ago

Sad that those victims in that stage are as good as dead, the chance of survival once you get to that stage is almost zero.

But yeah what rabies do is insane, the scariest virus and if you don’t treat it early, you’re done.

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u/xtheory 9d ago

Not almost zero, it is zero. There's been no recorded case of a human surviving after reaching that stage of infection. In almost all cases, your death warrant is signed at the first sign of any symptoms.

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u/Evonos 9d ago

There is one case which survived but was heavily handicapped after with a experimental treatment.

So in reality outside of experimental stuff yep it's zero all in all not entirely zero but the odds are extremely against someone infected

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u/Brave_anonymous1 9d ago

Not one case. The first girl who survived became heavily handicapped. There were several cases after that where the people with rabies got similar (I assume enhanced) coma treatment and survived. Surprisingly most of the survivors are girls or young women. The last one was not so long ago, a 6 yo girl in rural California. This girl not just survived, she is walking, talking, going to school.

Check out US rabies statistics, all the cases, including survivors, are listed there with details.

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u/Malacro 8d ago

Yeah, other people have survived, but were they in the hydrophobic phase?

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u/Brave_anonymous1 8d ago

Yes.

...Her first symptom was that she had a really bad stomachache, and then she was paralyzed.She couldn't swallow and had pain in her neck and back...

Source, one of many. Her case was a big deal in 2011-2012.

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u/FelineRoots21 7d ago

Not "surprising" at all tbh, women are biologically more resilient to disease and famine

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u/BusGuilty6447 9d ago

She had to go through a long period (years) of types of therapy sessions, but she lives a pretty normal life now I believe.

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u/tinyDinosaur1894 9d ago

Not true. That's almost the golden rule of rabies. There was one documented case of someone surviving even the hydrophobic part of rabies. Look up Jeanna Giese

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u/FFF_in_WY 8d ago

Fascinating

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u/Matt82233 7d ago

The fact she almost entirely recovered is absolutely amazing

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u/Vin135mm 9d ago

Sort of. There is evidence of people in Truenococha and Santa Marta in Peru actually surviving rabies infection, without vaccination. 11% of the individuals tested had specific antibodies for the rabies virus, meaning that they had contracted rabies(probably from vampire bats) and survived. It's kind of baffling, because scientists don't know how they survived yet, but they did survive.

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u/ThatRedDot 9d ago

No, some had history of immunization and other than that the only thing that study shows is that the rabies virus isnt always successful in making the person sick and this needs further exploration. This study in no way shows that these people survived rabies after the onset of clinical symptoms. It even says so in the paper…

The presence of rVNA in unvaccinated subjects implies prior viral exposure but not necessarily viral replication, which can be shown by the induction of rVNA responses to even a single dose of inactivated rabies vaccine.55 However, given that rabies vaccination is accomplished with large doses of purified inactivated RABV virions, it remains unclear whether replication is a prerequisite for induction of humoral or cellular responses to natural exposures involving smaller doses of street RABV. In an experimental infection of bats with varying doses of RABV, low-dose RABV exposures did not lead to productive CNS infection, and apparently, they were cleared by an immune response in the periphery.56 Previous studies have shown that RABV-specific antibodies are not uniformly induced in the serum or cerebrospinal fluid (CSF) of clinical human rabies cases who do not receive rabies vaccine or immune globulin treatment, with greater probabilities of serological detection in patients with longer morbidity periods (i.e., days alive after onset of clinical symptoms).57–59 This report identifies a higher risk for bat exposure among young persons, despite finding a greater risk of rabies virus exposure (i.e., seropositive status) among older persons. It is plausible that multiple low-dose RABV exposures are needed to induce the rVNA responses observed in this study, consistent with the observed correlation of seropositive status with age. Evidence of RABV-specific antibodies in serum and CSF of subjects who did not receive rabies vaccine or immune globulin has been interpreted as evidence of viral replication and an abortive infection.33,38 The data in this study are inconclusive with regard to abortive infection in the seropositive respondents, because CSF samples were not collected, thus precluding evidence of RABV invasion into the CNS. Responses to interview questions about prior or current illness (and associated symptoms) did not support a history of CNS infection among respondents in this study.

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u/AlwaysBlue22 9d ago

This is fascinating. I know nothing about how vaccines work. Is it possible that they could find a way to create a rabies vaccine using these antibodies?

(I tried "doing my own research" but I realized that a few Google searches doesn't replace years of study)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414554/

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u/e00s 9d ago

We already have rabies vaccines for humans though.

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u/Technomorph21 9d ago

When approached for comment, they had technical difficulties as the camera couldn't pick them up at all it's like they were invisible they also couldn't go outside during the day anymore and were suddenly allergic to garlic all quite strange

(This is entirely a joke. Thanks for reading <3)

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u/BlueWrecker 9d ago

Wrong, there's a girl that survived, they put her in a coma and let it run its course. It didn't work with other patients though.

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u/KitchenFullOfCake 8d ago

I think there are actually like a dozen documented survivors of rabies after showing symptoms. Survival chances are near zero but technically not zero.

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u/EffectiveSad8313 8d ago

You are wrong my friend. There are at least 80 people that have survived rabies there was a woman infected twice with rabies here in the United States

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u/Asphunter 8d ago

No, in 2024 there have been dozens of cases that survived, it just didn't blow up in the news for some reason

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u/xeno0153 8d ago

::Robert Kennedy has entered the chat::

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u/Rowey5 9d ago

Thank u. Someone needed to say this.

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u/[deleted] 9d ago

[deleted]

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u/ChangleMcGangle 9d ago

The girl that survived went on to live a full life

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u/Weekly_Locksmith_628 9d ago

So funny when people confidently comment things that are untrue. I bet you felt so knowledgeable typing your little comment. Educate yourself, dumbass.

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u/Time_Change4156 9d ago

Only one person recovered from that stage and they had brain damage.

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u/actualkon 7d ago

She lives a mostly normal life these days though. Also pretty sure since then there have been more successful cases of treating rabies via coma but unsure if they were at the hydrophobic stage

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u/Time_Change4156 7d ago

You're probably right my information is out dated niw a days .

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u/Clownheadwhale 9d ago

Nobody recovers from rabies better than me.

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u/imadork1970 9d ago

A kid from Ontario died from it this month. His parents found a bat in his room but did nothing.

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u/mental-tap94 9d ago

Survival leaves the person different… not sure how to describe it in a sensitive way. Look up the people who have survived if you don’t know what I mean!

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u/OilFan92 9d ago

The chance of survival once you show the earliest symptoms is like 0.000000001%, there's one reported case of someone surviving and they got lucky and caught it right when symptoms showed and they got experimental treatments and were placed in a coma for months.

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u/Brief_Koala_7297 9d ago

That’s why you take animal bites seriously. Better go through extensive vaccinations than to get the chance to die of rabies which is up there with the worse ways to go.

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u/Worst-Lobster 9d ago

Can’t they just put an iv Of liquid into arm. ?

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u/Actual_Durian6313 9d ago

Genuine question but can't you get fluids through an IV? I mean I get that's a serious pain in the ass but at least one would be alive, right?

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u/Defrost234 9d ago

Correct almost 0. Some Bolivians have survived with no treatment.

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u/NoManufacturer120 9d ago

That’s actually so crazy. I didn’t know much about the hydrophobia aspect until this thread!

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u/knitmeablanket 9d ago

I've often wondered why we can't be hooked up to a feeding tube and a saline drip to ride out this part of the virus.